Your doctor may decrease your dose if you have sleep apnea stop breathing for short periods during sleep while using this medicine. Using this medicine while you are pregnant may cause neonatal withdrawal syndrome in your newborn baby.
Check with your doctor right away if your baby has an abnormal sleep pattern, diarrhea, a high-pitched cry, irritability, shakiness or tremors, weight loss, vomiting, or fails to gain weight. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine. Tramadol is highly metabolized in the body. Some people change tramadol to a stronger product O-desmethyltramadol more quickly than others.
These individuals are called "ultra-rapid metabolizers of tramadol". Contact your doctor immediately if you experience extreme sleepiness, confusion, or shallow breathing. These symptoms may indicate that you are an "ultra-rapid metabolizer of tramadol. Children may be especially sensitive to this effect eg, serious breathing problems, death.
Do not give this medicine to:. If a nursing mother is an ultra-rapid metabolizer of tramadol, it could lead to an overdose in the nursing baby and cause very serious side effects. Check with your doctor right away if you or your child have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there.
These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body.
This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. Make sure your doctor knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless.
Also tell your doctor if you have any sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Let your doctor know if you or anyone in your family has bipolar disorder manic-depressive disorder or has tried to commit suicide. This medicine may cause serious allergic reactions, including anaphylaxis, angioedema, or certain skin conditions eg, Stevens-Johnson syndrome, toxic epidermal necrolysis.
These reactions can be life-threatening and require immediate medical attention. Call your doctor right away if you or your child have a rash, itching, blistering, peeling, or loosening of the skin, fever or chills, cough, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, trouble breathing or swallowing, unusual tiredness or weakness, or any swelling of your hands, face, mouth, or throat while you are using this medicine.
This medicine may cause some people to become drowsy, dizzy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. This medicine may cause adrenal gland problems. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This site complies with the HONcode standard for trustworthy health information: verify here.
This content does not have an English version. This content does not have an Arabic version. See more conditions. Products and services. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information. Please try again. QT prolongation is a serious condition affecting the heart rhythm. On an electrocardiogram of the heart, the QT interval represents a portion of the electrical activity during the heartbeat. Some drugs, such as tramadol, can cause QT prolongation.
When a person has a prolonged QT interval, they may experience serious heart problems. They may have an irregular heartbeat, which can become life threatening. In most cases of QT prolongation related to tramadol, a person has taken tramadol with other drugs that prolong the interval. Although the combination of QT-prolonging drugs can be dangerous, some people are born with long QT syndrome. These people should let their doctor know about their condition before taking tramadol.
Tramadol can interact with several medications, such as benzodiazepines and serotonergic drugs. Benzodiazepines are drugs that reduce anxiety and relax the muscles. People use them to treat anxiety and insomnia. If someone is already taking a benzodiazepine medication such as lorazepam or alprazolam, also taking tramadol can result in sedation, respiratory depression, coma, and even death. People who are taking serotonergic drugs should use tramadol carefully because of the risk of serotonin syndrome.
The following table lists serotonergic drug classes :. People taking tramadol should report any side effects to their doctor. By discussing the benefits and risks of the medication, a doctor can help a person find the most appropriate medicine at the lowest effective dosage.
Anyone having difficulty breathing or experiencing any symptoms of serotonin syndrome must seek immediate medical care. According to a World Health Organization WHO report on tramadol, clinical data in adults suggests that the drug has a low potential for dependence. People may, however, become dependent on tramadol when taking it for more than a few weeks or months. People with a history of drug misuse are more at risk of developing a dependence on tramadol.
In one case study , a year-old male with no history of substance misuse went to the emergency room to get help for tramadol addiction. His tramadol treatment began about 2 years earlier. He was taking up to mg per day and was unable to stop taking it without experiencing withdrawal symptoms.
Tramadol is an opioid pain medication. It also acts on brain chemicals called serotonin and norepinephrine to relieve moderate to severe pain. Tramadol is not safe for everyone. Children under 12 years old should not take tramadol, and those aged 12—18 should use caution when taking it. Some people may experience mild to severe side effects when taking tramadol. Some drug interactions can occur with tramadol, and the effects can be severe.
Although it has a low potential for dependence, the Drug Enforcement Administration DEA control the distribution of tramadol.
Clonazepam and Xanax both belong to a class of drugs called benzodiazepines. They are quite similar, but people use them them for different reasons….
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