The amount of blood taken depends on the needs of the research project, but will range from 40 to ml. Your body will need only a couple of days to replace ml of blood. Most people can donate regularly. If you indicate that you would be willing to give future blood donations, your name and contact details will be kept on a database for blood donation requests once every 3 months 4 times per year.
If you have a complaint about any aspect of the research, contact the Standing Committee on Ethics in Research on Humans via the Ethics and Compliance Team. If you agree to participate in a blood research project, you must sign a consent form. The exact content of the form will vary between projects, but it may be a statement that includes details such as:.
This page has been produced in consultation with and approved by:. A person with amyloidosis produces aggregates of insoluble protein that cannot be eliminated from the body. When a person is anaemic, the red blood cells have to work harder to get oxygen around the body. An aneurysm may have no symptoms until it is either very large or it ruptures. An appendectomy is usually carried out on an emergency basis to treat appendicitis.
Most people can resume normal activities around three weeks after an arthroscopy. Content on this website is provided for information purposes only. Information about a therapy, service, product or treatment does not in any way endorse or support such therapy, service, product or treatment and is not intended to replace advice from your doctor or other registered health professional. The information and materials contained on this website are not intended to constitute a comprehensive guide concerning all aspects of the therapy, product or treatment described on the website.
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The State of Victoria and the Department of Health shall not bear any liability for reliance by any user on the materials contained on this website. Skip to main content. Blood and blood vessels. Home Blood and blood vessels. Blood donation. Actions for this page Listen Print. Summary Read the full fact sheet.
On this page. Blood groups Who can donate blood? How blood donation works Types of blood donation Products made from whole blood Products made from blood plasma Blood donation for medical research Blood donation requirements for medical research Where to get help.
Who can donate blood? Blood donation requirements To donate blood, Lifeblood donors must: Be healthy and not suffering from a cold , flu or other illness at the time of donation.
Be aged between 18 and 75 years other rules may apply if you are a current donor. Weigh at least 50kg. Have normal temperature and blood pressure. Meet guidelines designed to protect both the donor and the people who will receive the blood. Blood donation and mad cow disease vCJD People who spent 6 months or more in the UK between and are currently unable to donate.
How blood donation works You can donate blood at various Australian Red Cross Lifeblood locations including blood donor centres or mobile units. A small amount of anticoagulant is added to stop the blood from clumping together in the machine. Inside the machine, your blood goes into a centrifuge where it gets spun around at high speeds. This separates the blood into layers: because plasma is lighter it ends up on the top layer, while the heavier red cells sink to the bottom. The machine is programmed to recognise the plasma, sending it into a special collection bag.
Every so often the red cells are flushed back into your arm. The whole cycle is repeated again, and again, until the desired amount of plasma depending on your weight, height, and so on has been obtained. Donated plasma can be frozen and kept for up to 12 months. This freshly frozen plasma is known, pretty sensibly, as fresh frozen plasma FFP for short.
Because it contains proteins which help with clotting, FFP can be used in clinical settings such as hospitals to treat major bleeding—for instance, in the case of a car accident or major operation. There are two further products which can be made from FFP and used to prevent bleeding. Cryoprecipitate is one of these. The main use of cryo-depleted plasma is for the treatment of a rare but often fatal blood disorder called Thrombotic Thrombocytopenic Purpura TTP. As important as FFP is for use in hospitals, most donated plasma is actually used for something else: the creation of plasma-based pharmaceutical products.
If you have a bleeding disorder or an immune deficiency, you probably already know the importance of medical products made from plasma. They contain high levels of antibodies against certain infections which can help to protect an individual against the disease, but these antibodies only last for a number of weeks. They do not provide long-term immunity. Tetanus immunoglobulin, for example, contains high levels of antibodies against tetanus and can be used to protect a person who has sustained a tetanus-prone wound but has not previously been vaccinated.
In these circumstances, the patient is usually given a tetanus immunoglobulin injection as well as the tetanus vaccine. This provides them immediate protection against tetanus as well as providing protection over the longer term.
So how exactly does donated plasma get turned into a whole variety of medical products? The first step in the fractionation process is testing the plasma for blood-borne viruses. Next, all the frozen plasma donations are put together and thawed out into a big plasma soup. The plasma is then passed through specialised stainless steel cylinders and separated into the various plasma products.
Any viruses in the plasma are then inactivated, with each type of plasma product having its own specific viral inactivation steps. Some of the other manufacturing steps also contribute to the viral safety of the products. Altogether, there are 15 medical products made in Australia using donated plasma. They fall into three main types: immunoglobulins, clotting factors, and albumin.
Immunoglobulins are used to treat immune disorders such as primary or acquired immune deficiency. Albumin is used to treat fluid loss or to supplement low albumin levels—for instance, where someone is suffering from shock due to blood loss.
And that injection my Rh negative colleague Amy will need if she has a baby? When it comes to the red stuff, most of us know that getting the wrong type of blood, say, in a transfusion, is not a good thing. Platelets A normal platelet count for adults ranges between , to , platelets per microliter. Oneblood Blog Subscribe to our blog to read inspiring stories and get the latest news.
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